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Biobanking Sciences in the era of Personalized Medicine

Published 21 May 2019 This interdisciplinary course is suitable for sociologist, scientists, lawyers among others, and will deal with topics in the frame of Biobanking such as AI and machine learning, common registers, data sharing in a European framework, personalized/precision medicine, and ethics in the future of Biobanking For more information and registration, click here.

https://www.lupop.lu.se/article/biobanking-sciences-era-personalized-medicine - 2025-01-30

Adolescent and young adult cancer survivors' perceptions of participating in a survey - Ethical and methodological considerations

Published 22 May 2019 The aim of this study was to understand patient-reported perception of participation in a population-based web-survey focusing on sensitive issues for adolescent and young adult cancer survivors. New publication in Eur J Oncol NursRead more here.

https://www.lupop.lu.se/article/adolescent-and-young-adult-cancer-survivors-perceptions-participating-survey-ethical-and - 2025-01-30

Development and Validation of a Novel Risk Score for In-Hospital Major Bleeding in Acute Myocardial Infarction:-The SWEDEHEART Score.

Published 23 May 2019 Bleeding risk stratification in acute coronary syndrome is of highest clinical interest but current risk scores have limitations. We sought to develop and validate a new in-hospital bleeding risk score for patients with acute myocardial infarction. New publication in Journal of the American Heart Association.Read more here

https://www.lupop.lu.se/article/development-and-validation-novel-risk-score-hospital-major-bleeding-acute-myocardial-infarction - 2025-01-30

Offspring Reports on Parental Place of Upbringing Is It Valid?

Published 24 May 2019 The present study includes questionnaire information on parental place of upbringing from two sources: the parents themselves and their offspring. We aimed to investigate the agreement between offspring’s and parent’s reporting of parental place of upbringing, which to our knowledge has not been investigated before New publication in Epidemiology.Read more here

https://www.lupop.lu.se/article/offspring-reports-parental-place-upbringing-it-valid - 2025-01-30

Causal Inference in Environmental Epidemiology Old and New Approaches

Published 27 May 2019 It has been argued that epidemiology is currently going through a methodologic revolution involving the “causal inference” movement.1,2 This proposes that observational studies should mimic key aspects of randomized trials, because this allows them to be rooted in counterfactual reasoning, which is said to formalize the natural way that humans think about causality. These new

https://www.lupop.lu.se/article/causal-inference-environmental-epidemiology-old-and-new-approaches - 2025-01-30

Prevalence of chronic hepatitis C virus infection among childhood cancer survivors in Stockholm, Sweden.

Published 28 May 2019 Childhood cancer survivors treated before 1992, when blood donor screening for hepatitis C virus (HCV) infection was introduced, are at risk of transfusion-transmitted HCV infection. A national HCV screening campaign targeting blood transfusion recipients was launched in Sweden in 2007-2010. New publication in Acta OncolRead more here.

https://www.lupop.lu.se/article/prevalence-chronic-hepatitis-c-virus-infection-among-childhood-cancer-survivors-stockholm-sweden - 2025-01-30

Mini Review on the Use of Clinical Cancer Registers for Prostate Cancer: The National Prostate Cancer Register (NPCR) of Sweden.

Published 29 May 2019 Given the increasing prevalence of cancer, it is vital to systematically collect data in order to monitor disease trends and quality of cancer care. For this purpose, clinical cancer registries have been developed in some countries. These registers are intended to be used as a basis for quality assurance and quality improvement, but they also constitute a rich resource of rea

https://www.lupop.lu.se/article/mini-review-use-clinical-cancer-registers-prostate-cancer-national-prostate-cancer-register-npcr-0 - 2025-01-30

Return to work after sickness absence: a register-based comparison of two indigenous population groups.

Published 31 May 2019 The objective of the article was to analyse how Finnish and Swedish speakers in Finland differ in health and labour market outcomes after sickness absence. Apart from many similarities, these two population groups differ in life expectancy and union stability and are supposed to be culturally distinct. Our analyses, therefore, help to shed light on the interrelation between c

https://www.lupop.lu.se/article/return-work-after-sickness-absence-register-based-comparison-two-indigenous-population-groups - 2025-01-30

Development and Validation of a Novel Risk Score for In-Hospital Major Bleeding in Acute Myocardial Infarction:-The SWEDEHEART Score

Published 3 June 2019 Background-Bleeding risk stratification in acute coronary syndrome is of highest clinical interest but current risk scores have limitations. We sought to develop and validate a new in-hospital bleeding risk score for patients with acute myocardial infarction. New publication in Web of Science.Read more here.

https://www.lupop.lu.se/article/development-and-validation-novel-risk-score-hospital-major-bleeding-acute-myocardial-infarction-0 - 2025-01-30

The short-term survival of total stemless shoulder arthroplasty for osteoarthritis is comparable to that of total stemmed shoulder arthroplasty: a Nordic Arthroplasty Register Association study.

Published 4 June 2019 The short-term survival of total stemless shoulder arthroplasty appears comparable with total stemmed shoulder arthroplasty, but longer observation time is needed to confirm whether they continue to perform equally. New publication in Journal of Shoulder and Elbow surgery.Read more here.

https://www.lupop.lu.se/article/short-term-survival-total-stemless-shoulder-arthroplasty-osteoarthritis-comparable-total-stemmed - 2025-01-30

Defining Evidence for Precision Medicine A Patient Is More Than a Set of Covariates

Published 5 June 2019 Precision medicine is the envisioned future model of health care in which treatments and care are tailored to the individual patient. The precision medicine slogan “One size does not fit all” stems from the fact that heterogeneity in treatment effects is common. Precision medicine research aims to find the best treatment for each patient through a better understanding of the

https://www.lupop.lu.se/article/defining-evidence-precision-medicine-patient-more-set-covariates - 2025-01-30

International variation in survival after out-of-hospital cardiac arrest: A validation study of the Utstein template.

Published 7 June 2019 Out-of-hospital cardiac arrest (OHCA) survival varies greatly between communities. The Utstein template was developed and promulgated to improve the comparability of OHCA outcome reports, but it has undergone limited empiric validation. We sought to assess how much of the variation in OHCA survival between emergency medical services (EMS) across the globe is explained by diff

https://www.lupop.lu.se/article/international-variation-survival-after-out-hospital-cardiac-arrest-validation-study-utstein-template-0 - 2025-01-30

Outcome after intravenous thrombolysis in patients with acute lacunar stroke: An observational study based on SITS international registry and a meta-analysis.

Published 10 June 2019 Intravenous thrombolysis (IVT) for lacunar stroke (LS) is debated, as the underlying pathophysiological mechanism may not be thrombogenic. New publication in Int J Stroke.Read more here

https://www.lupop.lu.se/article/outcome-after-intravenous-thrombolysis-patients-acute-lacunar-stroke-observational-study-based-sits - 2025-01-30

How to Maintain Good Quality Register Systems?

Published 11 June 2019 Good health information is essential for good governance and national health information systems have a central function in the health systems. Decision makers and health professionals need a systematic way of increasing their ability to access and synthesise the growing volume of information as a part of public health, clinical medicine and management of health care service

https://www.lupop.lu.se/article/how-maintain-good-quality-register-systems - 2025-01-30

The Back Pain and Movement (B-PAM) registry; a study protocol

Published 12 June 2019 Low back pain (LBP) is a ubiquitous, heterogeneous disorder that affects most people at some point in their lives. The efficient management of LBP remains elusive, with direct and indirect costs attributed to LBP surpassing many other common conditions. An emphasis on a structural basis of LBP often fails to recognize movement, specifically patterns of movement that may prov

https://www.lupop.lu.se/article/back-pain-and-movement-b-pam-registry-study-protocol - 2025-01-30

An Improvement in Estimation of the Standard Error for the Natural Direct Effect in Causal Mediation Analysis

Published 13 June 2019 Mediation analysis serves as a crucial tool to perform causal inferences on the relationship among an exposure, a mediator, and an outcome. Methods for statistical inference of the parameter estimates of the mediation effects are limited and need improvement, relying on Bayesian, bootstrapping or Delta methods. New publication in EpidemiologyRead more here

https://www.lupop.lu.se/article/improvement-estimation-standard-error-natural-direct-effect-causal-mediation-analysis - 2025-01-30

A descriptive review of variable selection methods in four epidemiologic journals: there is still room for improvement

Published 14 June 2019 A review of epidemiological papers conducted in 2009 concluded that several studies employed variable selection methods susceptible to introduce bias and yield inadequate inferences. Many new confounder selection methods have been developed since then. The goal of the study was to provide an updated descriptive portrait of which variable selection methods are used by epidemi

https://www.lupop.lu.se/article/descriptive-review-variable-selection-methods-four-epidemiologic-journals-there-still-room - 2025-01-30